Postdoctoral research position at Department of Clinical Immunology, Zealand University Hospital, Zealand Region

Position as postdoctoral researcher at the Department of Clinical Immunology, Zealand University Hospital, Zealand Region

We have a vacant position as postdoctoral researcher from 2024-08-01 to conduct an 11 months study on mesenchymal stem cell (MSC) immunology, MSC product development, and early biomarkers in pancreatic cancer.

The position is temporary and runs for 11 months. The position is 37 hours per week, with work hours between 08:00 – 15:24 on weekdays. However, the research project can also require that you work on evenings/weekends.

The position is at the Department of Clinical Immunology in Næstved. However, in 2025 we will move the department to Køge. The research will aim at determining the importance of HLA-F in MSC immunology and establishing MSC products for patient treatment. We have already developed and designed most of the work flow and projects for this treatment but still need some quality control in place. The study is conducted in close collaboration with Department of Science and Environment, Roskilde University and Department of Orthopedic Surgery, Odense University Hospital.

The postdoctoral researcher shall run the project, perform quality control, prepare the MSC production for approval. In addition the postdoctoral researcher shall conduct molecular biology analyses on MSC cellular and immunological functions, miRNA analyses in pancreatic cancer as well as publishing the results. The postdoctoral researcher is free to decide on and pursue specific research angles within the scope of this work. The postdoctoral researcher will collaborate with other researchers within the research group at the Department of Clinical Immunology, Zealand University Hospital.

The specific deliverables within MSC production are:

• Updating all data and documentation in the quality control system (D4) incl. the MSC expansion protocols
• Defining the QP for the GMP production
• Validation of BactAlert according to EU regulation
• Establishing Mycoplasma test according to EU regulation
• Revalidation of Flow analysis on NovoCyte
• All processes has to be validated x3 according to EU regulation
• Repeating aseptic process monitoring and establishing system for repeated QC of these

The specific deliverables within pancreatic cancer are:

• Identifying and validating circulating miRNA markers in pancreatic cancer
• Dissemination of results

We have the following wishes for the candidate:

You have experience with the following:

• Molecular biology
• Stem cell biology and immunology
• Statistical analyses in R or similar programs.

Your education and background:

• A Ph.D. degree in medical or natural science preferably with focus on stem cells and molecular biology.
• At least one submitted or accepted first authorship in a relevant journal
• Excellent collaborative skills
• A positive and motivating attitude making you an excellent role model
• Diligence and intellectual flexibility as required for an academic position
• An open and positive mind that actively contributes to the infrastructure and the success of the research team

We offer you

- A position in a large organisation with around 120 employees, of whom 50 will be in Næstved.

- A workplace with many new challenges and a good work environment.

- A growing and international research environment within stem cell research, immunology, chronic inflammatory diseases, biomarkers, and genetics.

- Highly qualified mentors within by professor Ole Birger Vesterager Pedersen and chief physician, Ph.D. Susanne Sækmose

- An active research environment with three other postdoc’s, several Ph.D. students, and close collaborations with Department of Science and Environment, Roskilde University as well as stem cell researchers at Odense University Hospital.